In 1953, Ancel Keys, compared levels of this disease in seven countries with the amounts of fat in those countries. And so was born the 'Diet-Heart' hypothesis, for the new disease was coronary heart disease.
First "heart health" cook books from the study released toward the end of the decade. The Mediterranean diet.
To reduce the risk of a heart attack, Ancel Keys recommended cutting down on the vegetable oils and margarines.
Keys A. Atheroesclerosis: a problem in newer public health. J Mt Sinai Hosp 1953; 20: 118-139.
Keys A. Seven countries: a multivariate analysis of death and coronary heart disease. London: Harvard University Press, 1980.